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Journal article

Conversion to sirolimus in kidney transplant recipients with squamous cell cancer and changes in immune phenotype.

Abstract:

BACKGROUND: Conversion to sirolimus from calcineurin inhibitor- (CNI), azathioprine- (AZA) and mycophenolate-based regimens reduces the risk of development of squamous cell carcinoma of the skin (SCC) in kidney transplant recipients (KTRs). Sirolimus conversion may also be protective by permitting beneficial changes in immune phenotype. It is not known how sirolimus will affect immune phenotype in KTRs with SCC. METHODS: Thirty-two KTRs with SCC were enrolled into this single-blinded randomi...

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Publication status:
Published

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Publisher copy:
10.1093/ndt/gfs474

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Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Role:
Author
Journal:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Volume:
28
Issue:
2
Pages:
462-465
Publication date:
2013-02-05
DOI:
EISSN:
1460-2385
ISSN:
0931-0509
URN:
uuid:24406cdf-671e-4bbe-a9c9-1a818a863ce6
Source identifiers:
367724
Local pid:
pubs:367724

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