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Journal article

Defining the HLA class I-associated viral antigen repertoire from HIV-1-infected human cells.

Abstract:

Recognition and eradication of infected cells by cytotoxic T lymphocytes is a key defense mechanism against intracellular pathogens. High-throughput definition of HLA class I-associated immunopeptidomes by mass spectrometry is an increasingly important analytical tool to advance our understanding of the induction of T-cell responses against pathogens such as HIV-1. We utilized a liquid chromatography tandem mass spectrometry workflow including de novo-assisted database searching to define the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/eji.201545890

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Target Discovery Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
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Department for International Development More from this funder
Nuffield Department of Medicine More from this funder
Instituto de Salud Carlos III More from this funder
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Publisher:
Wiley Publisher's website
Journal:
European Journal of Immunology Journal website
Volume:
46
Issue:
1
Pages:
60-69
Publication date:
2016-01-01
Acceptance date:
2015-10-08
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Source identifiers:
574957
Language:
English
Keywords:
Pubs id:
pubs:574957
UUID:
uuid:243ef5ee-387a-4732-892d-5fd80fe9f425
Local pid:
pubs:574957
Deposit date:
2016-02-19

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