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Journal article

Peptides: Minimal drug surrogates to interrogate and interfere with protein function

Abstract:

The interactome in normal and disease cells is a key area for study and therapeutic targeting, yet few molecules have been developed that can interfere with protein-protein interactions within cells. A variety of options are being examined to target protein-protein interfaces in simple and in multi protein complexes. The work of Hamilton and colleagues has developed approaches to the synthesis of proteomimetics for this purpose and thus recognized novel scaffolds can be critical reagents to p...

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Publisher copy:
10.1039/c3md00142c

Authors


Journal:
MedChemComm
Volume:
4
Issue:
9
Pages:
1218-1221
Publication date:
2013-09-05
DOI:
EISSN:
2040-2511
ISSN:
2040-2503
URN:
uuid:243aebb7-7f38-4735-903f-8a3ca5b6537d
Source identifiers:
426806
Local pid:
pubs:426806
Language:
English

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