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Journal article

Human genetic susceptibility to infectious disease.

Abstract:

Recent genome-wide studies have reported novel associations between common polymorphisms and susceptibility to many major infectious diseases in humans. In parallel, an increasing number of rare mutations underlying susceptibility to specific phenotypes of infectious disease have been described. Together, these developments have highlighted a key role for host genetic variation in determining the susceptibility to infectious disease. They have also provided insights into the genetic architect...

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Publication status:
Published

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Publisher copy:
10.1038/nrg3114

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute, Biomedical Research Centre
Role:
Author
Journal:
Nature reviews. Genetics
Volume:
13
Issue:
3
Pages:
175-188
Publication date:
2012-03-05
DOI:
EISSN:
1471-0064
ISSN:
1471-0056
URN:
uuid:2438aa07-5c14-4954-b05b-45ce4a665b3a
Source identifiers:
254257
Local pid:
pubs:254257

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