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Journal article

A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults

Abstract:

Background There is currently no licensed antiviral drug for treatment of dengue. Chloroquine (CQ) inhibits the replication of dengue virus (DENV) in vitro. Methods and Findings A double-blind, randomized, placebo-controlled trial of CQ in 307 adults hospitalized for suspected DENV infection was conducted at the Hospital for Tropical Diseases (Ho Chi Minh City, Vietnam) between May 2007 and July 2008. Patients with illness histories of 72 hours or less were randomized to a 3-day course of CQ ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pntd.0000785

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More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Neglected Tropical Diseases Journal website
Volume:
4
Issue:
8
Pages:
ARTN e785
Publication date:
2010-08-10
Acceptance date:
2010-07-10
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Language:
English
Keywords:
UUID:
uuid:2433683f-ee12-4378-970d-fc70734f4bcb
Local pid:
pubs:66134
Source identifiers:
66134
Deposit date:
2012-12-19

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