Streptococcus pneumoniae causes significant morbidity and mortality especially in children. Some pneumococcal protein antigens can protect mice against infection. Little information is available concerning the nature of naturally acquired protective immunity to pneumococci in humans induced by these antigens. This study investigates the relationships between systemic and local antibody production and carriage in children. Children undergoing adenoidectomy (n=112, ages 2-12 years) wer... Expand abstract
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- Peer reviewed
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- Wiley-VCH Verlag GmbH & Co.
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- The full-text of this article is not currently available in ORA, but you may be able to access the article via the publisher copy link on this record page. Citation: Zhang, Q., Bernatoniene, J., Bagrade, L., Pollard, A., Mitchell, T., Paton, J. and Finn, A. (2006), Serum and mucosal antibody responses to pneumococcal protein antigens in children:relationships with carriage status. European Journal of Immunology, 36(1): 46–57. doi: 10.1002/eji.200535101. © 2006 Wiley-VCH Verlag GmbH & Co.
Serum and mucosal antibody responses to pneumococcal protein antigens in children: relationships with carriage status
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