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Pharmacokinetics of piperaquine in pregnant women in Sudan with uncomplicated Plasmodium falciparum malaria.

Abstract:

The pharmacokinetic properties of piperaquine were investigated in 12 pregnant and 12 well-matched, non-pregnant women receiving a three-day oral fixed dose combination regimen of dihydroartemisinin and piperaquine for treatment of uncomplicated Plasmodium falciparum at New Halfa Hospital in eastern Sudan. Frequent venous plasma samples were drawn from the patients over a 63-day period and a complete concentration-time profile was collected for 7 pregnant and 11 non-pregnant patients. Piperaq...

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Publication status:
Published

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Publisher copy:
10.4269/ajtmh.2012.11-0410

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
American journal of tropical medicine and hygiene More from this journal
Volume:
87
Issue:
1
Pages:
35-40
Publication date:
2012-07-01
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
Language:
English
Keywords:
Pubs id:
pubs:341062
UUID:
uuid:24285bf2-f24c-4797-b186-855015b3f48d
Local pid:
pubs:341062
Source identifiers:
341062
Deposit date:
2012-12-19

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