Journal article
The prospects of an active vaccine against asthma targeting IL-5
- Abstract:
-
Allergen-specific T helper type 2 (Th2) responses followed by eosinophilic inflammation of the lung are important causes of allergic asthma. Interleukin-5 (IL-5) is a master regulator of eosinophil differentiation as well as activation. Blocking IL-5 using monoclonal antibodies (mAbs) against IL-5 is a powerful way to improve asthmatic symptoms in patients with an eosinophilic component of the disease. We have previously shown that vaccination against IL-5 can abrogate eosinophilic inflammati...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
Actions
Access Document
- Files:
-
-
(pdf, 233.6KB)
-
- Publisher copy:
- 10.3389/fmicb.2018.02522
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Microbiology Journal website
- Volume:
- 9
- Issue:
- OCT
- Pages:
- 2522
- Publication date:
- 2018-10-24
- Acceptance date:
- 2018-10-03
- DOI:
- EISSN:
-
1664-302X
- ISSN:
-
1664-302X
- Pubs id:
-
pubs:938545
- URN:
-
uri:24248bb2-2161-4596-9f07-f4c1ba76923e
- UUID:
-
uuid:24248bb2-2161-4596-9f07-f4c1ba76923e
- Local pid:
- pubs:938545
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- Bachmann et al
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 Bachmann, El-Turabi, Fettelschoss-Gabriel and Vogel. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
If you are the owner of this record, you can report an update to it here: Report update to this record