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Systematic review of the scrub typhus treatment landscape: Assessing the feasibility of an individual participant-level data (IPD) platform

Abstract:
Background Scrub typhus is an acute febrile illness caused by intracellular bacteria from the genus Orientia. It is estimated that one billion people are at risk, with one million cases annually mainly affecting rural areas in Asia-Oceania. Relative to its burden, scrub typhus is understudied, and treatment recommendations vary with poor evidence base. These knowledge gaps could be addressed by establishing an individual participant-level data (IPD) platform, which would enab... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pntd.0009858

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Role:
Author
ORCID:
0000-0001-8705-9176
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Role:
Author
ORCID:
0000-0002-6333-0109
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Role:
Author
ORCID:
0000-0003-3449-7142
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Role:
Author
ORCID:
0000-0003-2892-3053
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Role:
Author
ORCID:
0000-0003-4417-0653
Publisher:
Public Library of Science
Journal:
PLoS Neglected Tropical Diseases More from this journal
Volume:
15
Issue:
10
Article number:
e0009858
Place of publication:
United States
Publication date:
2021-10-14
Acceptance date:
2021-09-28
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Pmid:
34648517
Language:
English
Keywords:
Pubs id:
1204331
Local pid:
pubs:1204331
Deposit date:
2021-12-22

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