Journal article icon

Journal article

Ag-catalyzed stereoselective aminosulfonylation of alkynes

Abstract:
A silver-catalyzed intermolecular aminosulfonylation of terminal alkynes with sodium sulfinates and TMSN3 is reported. This three component reaction proceeds through sequential hydroazidation of the terminal alkyne, and addition of a sulfonyl radical to the resultant vinyl azide. The method enables the stereoselective synthesis of a wide range of β-sulfonyl enamines without electron-withdrawing groups on the nitrogen atom, which are found to be suitable for a variety of further transformations.
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1002/anie.201705122

Authors


More by this author
Institution:
University of Oxford
Oxford college:
Jesus College
Role:
Author
More from this funder
Funding agency for:
Anderson, E
Grant:
EP/M019195/1
Publisher:
Wiley Publisher's website
Journal:
Angewandte Chemie International Edition Journal website
Volume:
56
Issue:
44
Pages:
13805-13808
Publication date:
2017-06-19
Acceptance date:
2017-06-17
DOI:
EISSN:
1521-3757
ISSN:
1433-7851
Source identifiers:
702100
Keywords:
Pubs id:
pubs:702100
UUID:
uuid:2419002c-8873-470f-b457-dae31e4f8408
Local pid:
pubs:702100
Deposit date:
2017-06-28

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP