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Journal article

Non-catalytic tyrosine-phosphorylated receptors.

Abstract:

Leukocytes play a critical role in recognizing and responding to infection and cancer. Central to this function is an array of cell-surface receptors that lack sequence homology. Many of these receptors have in common the fact that their signaling involves phosphorylation of cytoplasmic domains by extrinsic tyrosine kinases. These non-catalytic tyrosine-phosphorylated receptors (NTRs) share a number of other features, including small size and optimal stimulation by surface-associated ligands....

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Publication status:
Published

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Publisher copy:
10.1111/imr.12008

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Goyette, J More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Immunological reviews
Volume:
250
Issue:
1
Pages:
258-276
Publication date:
2012-11-05
DOI:
EISSN:
1600-065X
ISSN:
0105-2896
URN:
uuid:23fa7733-cd15-4d85-adf9-5566469abb2f
Source identifiers:
353932
Local pid:
pubs:353932

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