- Abstract:
-
OBJECTIVE: To finer linkage-map a primary osteoarthritis (OA) susceptibility locus as a prerequisite to linkage disequilibrium/association analysis. METHODS: A 50-cM interval of chromosome 11q that we had previously identified as harboring susceptibility to hip OA in a female sibling-pair cohort was subjected to finer linkage mapping. Thirty-five microsatellite markers with a mean marker interval of 1.4 cM were genotyped in 146 families containing female sibling pairs who were concordant for...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/art.10412
-
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- Journal:
- Arthritis and rheumatism
- Volume:
- 46
- Issue:
- 7
- Pages:
- 1780-1783
- Publication date:
- 2002-07-05
- DOI:
- EISSN:
-
1529-0131
- ISSN:
-
0004-3591
- URN:
-
uuid:23d4c93e-907f-4328-a81b-8b2c61ba9642
- Source identifiers:
-
107292
- Local pid:
- pubs:107292
- Language:
- English
- Keywords:
- Copyright date:
- 2002
Journal article
Finer linkage mapping of primary hip osteoarthritis susceptibility on chromosome 11q in a cohort of affected female sibling pairs.
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