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HIV-1 recombination: an experimental assay and a phylogenetic approach.

Abstract:

The generation of genetic diversity is a fundamental characteristic of HIV-1 replication, allowing the virus to successfully evade the immune response and antiviral therapies. Although mutations are the first step towards diversity, mixing of the mutations through the process of recombination increases the variation and allows for the faster establishment of advantageous strains within the viral population. Therefore, studying recombination of HIV-1 provides insights into not only the mechani...

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Publisher copy:
10.1007/978-1-59745-170-3_7

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Methods in molecular biology (Clifton, N.J.) More from this journal
Volume:
485
Pages:
87-105
Publication date:
2009-01-01
DOI:
EISSN:
1940-6029
ISSN:
1064-3745
Language:
English
Keywords:
Pubs id:
pubs:228613
UUID:
uuid:23c85b2d-0baa-4ada-a0c0-0d4e4d315585
Local pid:
pubs:228613
Source identifiers:
228613
Deposit date:
2013-02-20

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