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Journal article

Human gene mapping using an X/autosome translocation.

Abstract:

Human fibroblasts containing a translocation between the X chromosome and chromosome 15 were fused with the 6-thioguanine-resistant mouse cell line, IR. Resulting hybrids, selected in HAT medium, retained the X/15 chromosome. Hybrids which were counterselected in 6-thioguanine lost this chromosome. The X-linked markers glucose-6-phosphate dehydrogenase (G6PD), phosphoglycerate kinase (PGK), and hypoxanthine phosphoribosyl transferase (HPRT), and the non-X-linked markers pyruvate kinase (PKM2)...

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Publication status:
Published

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Publisher copy:
10.1007/bf01542626

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Publisher:
Kluwer Academic Publishers-Plenum Publishers
Journal:
Somatic cell genetics
Volume:
2
Issue:
2
Pages:
125-140
Publication date:
1976-03-05
DOI:
EISSN:
1572-9931
ISSN:
0098-0366
URN:
uuid:23bb3e21-9124-401b-88aa-73ef7c826474
Source identifiers:
487547
Local pid:
pubs:487547

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