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Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy.

Abstract:

Multispecific CD8(+) T-cell responses are thought to be important for the control of acute hepatitis C virus (HCV) infection, but to date little information is actually available on the breadth of responses at early time points. Additionally, the influence of early therapy on these responses and their relationships to outcome are controversial. To investigate this issue, we performed comprehensive analysis of the breadth and frequencies of virus-specific CD8(+) T-cell responses on the single ...

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Publication status:
Published

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Journal:
Journal of virology
Volume:
79
Issue:
20
Pages:
12979-12988
Publication date:
2005-10-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:23a8b100-4a2c-4d0d-91a8-5eaaf364b3a7
Source identifiers:
24289
Local pid:
pubs:24289

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