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Journal article

Association of cardiovascular risk factors with MRI indices of cerebrovascular structure and function and white matter hyperintensities in young adults

Abstract:

Importance: Risk of stroke and brain atrophy in later life relate to levels of cardiovascular risk in early adulthood. However, it is unknown whether cerebrovascular changes are present in young adults.

Objective: To examine relationships between modifiable cardiovascular risk factors and cerebrovascular structure, function, and white matter integrity in young adults.

Design, Setting, and Participants: A cross-sectional observational study of 125 young adults (aged 18-40...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1001/jama.2018.11498

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
ORCID:
0000-0002-4978-8965
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0001-8258-0659
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More from this funder
Funding agency for:
Williamson, W
Grant:
105741/Z/14/Z
Publisher:
American Medical Association Publisher's website
Journal:
JAMA Journal website
Volume:
320
Issue:
7
Pages:
665-673
Publication date:
2018-08-21
Acceptance date:
2018-07-22
DOI:
EISSN:
1538-3598
ISSN:
0098-7484
Pmid:
30140877
Source identifiers:
911288
Language:
English
Pubs id:
pubs:911288
UUID:
uuid:23929ad8-c4a8-47e5-90f1-a77fc877f13d
Local pid:
pubs:911288
Deposit date:
2018-10-10

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