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Journal article

3D finite element formulation for mechanical-electrophysiological coupling in axonopathy

Abstract:

Traumatic injuries to the central nervous system (brain and spinal cord) have recently been put under the spotlight because of their devastating socio-economical cost. At the cellular scale, recent research efforts have focussed on primary injuries by making use of models aimed at simulating mechanical deformation induced axonal electrophysiological functional deficits. The overwhelming majority of these models only consider axonal stretching as a loading mode, while other modes of deformatio...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cma.2018.09.006

Authors


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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Role:
Author
More from this funder
Name:
Engineering and Physical Sciences Research Council
Funding agency for:
Bianchi, F
Grant:
1514540
More from this funder
Name:
European Research Council - Seventh Framework Programme
Funding agency for:
Kwong, M
Jérusalem, A
Grant:
306587
306587
More from this funder
Name:
China Regenerative Medicine Limited
Funding agency for:
Ye, H
Publisher:
Elsevier
Journal:
Computer Methods in Applied Mechanics and Engineering More from this journal
Volume:
346
Pages:
1025-1050
Publication date:
2018-09-22
Acceptance date:
2018-09-04
DOI:
EISSN:
1879-2138
ISSN:
0045-7825
Keywords:
Pubs id:
pubs:920124
UUID:
uuid:239212d3-744d-41bc-a818-d5c116680ba4
Local pid:
pubs:920124
Source identifiers:
920124
Deposit date:
2018-09-17

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