Cannabinoid 1 receptors are expressed by nerve growth factor- and glial cell-derived neurotrophic factor-responsive primary sensory neurones.

Journal article

Expression of the cannabinoid 1 (CB1) receptor and its regulation were studied in the different nociceptive and non-nociceptive sub-populations of cultured primary sensory neurones of adult rats. Bandairaea simplicifolia isolectin B4 (IB4) binding and calcitonin gene-related peptide (CGRP) immunostaining were used to distinguish between the glial cell-derived neurotrophic factor (GDNF)- and nerve growth factor (NGF)-responsive nociceptive and the non-nociceptive primary sensory neurones while...

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Authors: Ahluwalia, J; Urban, L; Bevan, S; Capogna, M; Nagy, I

• Publication status: Published
• Journal: Neuroscience
• Volume: 110
• Issue: 4
• Pages: 747-753
• Publication date: 2002-01-01
• DOI: 10.1016/S0306-4522(01)00601-7
• EISSN: 1873-7544
• ISSN: 0306-4522
• Language: English
• Keywords: Glial Cell Line-Derived Neurotrophic Factor; Cell Size; Nerve Tissue Proteins; Pain; Ganglia, Spinal; Nerve Growth Factors; Nerve Growth Factor; Neurons, Afferent; Immunohistochemistry; Animals; Nociceptors; Gene Expression; Calcitonin Gene-Related Peptide; Lectins; Rats; Cells, Cultured; Receptors, Drug; Receptors, Cannabinoid