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Journal article

Rapid switching to multiple antigenic and adhesive phenotypes in malaria.

Abstract:

Adhesion of parasitized erythrocytes to post-capillary venular endothelium or uninfected red cells is strongly implicated in the pathogenesis of severe Plasmodium falciparum malaria. Neoantigens at the infected red-cell surface adhere to a variety of host receptors, demonstrate serological diversity in field isolates and may also be a target of the host-protective immune response. Here we use sequential cloning of P. falciparum by micromanipulation to investigate the ability of a parasite to ...

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Publication status:
Published

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Publisher copy:
10.1038/357689a0

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Journal:
Nature More from this journal
Volume:
357
Issue:
6380
Pages:
689-692
Publication date:
1992-06-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Language:
English
Keywords:
Pubs id:
pubs:26964
UUID:
uuid:238599a0-845d-460b-99a5-920ad52b686e
Local pid:
pubs:26964
Source identifiers:
26964
Deposit date:
2012-12-19

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