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Plasmodium falciparum glycolipid synthesis: constant and variant molecules of isolates and of strains with differing knob and cytoadherence phenotype.

Abstract:

Plasmodium falciparum-infected erythrocytes were metabolically labeled with tritiated glucosamine. Lipid extracts were analyzed by high-performance thin-layer chromatography to compare labeled molecules of eleven isolates from patients, six cytoadherent in vitro strains, and two knobbed and two knobless strains from Aotus monkeys. Up to nineteen labeled bands were identified. Glycolipid GL1, previously identified in Malayan Camp, was present in all isolates and strains. Other molecules, betwe...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Journal:
The Journal of protozoology
Volume:
35
Issue:
1
Pages:
169-172
Publication date:
1988-02-05
DOI:
ISSN:
0022-3921
URN:
uuid:234188d0-4c8e-4a76-8db7-f16c2702171f
Source identifiers:
184975
Local pid:
pubs:184975

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