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Thesis

Genomic epidemiology of meningococcal vaccine antigens in the United Kingdom

Abstract:

Vaccination against Neisseria meningitidis remains the optimal means to prevent invasive meningococcal disease (IMD), an important cause of septicaemia and meningitis disproportionately affecting infants and young children. Subcapsular protein-based vaccines were developed to offer broad protection against genetic lineages of meningococci responsible for endemic capsular group B IMD. As meningococci solely colonise the human oropharynx, the inherent variation in surface proteins p...

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Department:
Department of Zoology

Contributors

Department:
University of Oxford
Role:
Supervisor
Department:
Sir William Dunn School of Pathology
Role:
Supervisor
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Grant:
109031/Z15/Z
Funding agency for:
Project
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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