Journal article
CD8 helps TCR catch slippery self pMHC
- Abstract:
- A new model proposes that an applied force allows the co-receptor CD8 and the kinase Lck to selectively stabilize TCR interactions with negatively selecting ligands, but not those with positively selecting ligands, during the negative selection of self-reactive thymocytes.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Accepted manuscript, pdf, 125.2KB)
-
- Publisher copy:
- 10.1038/s41590-018-0261-5
Authors
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Immunology Journal website
- Volume:
- 19
- Issue:
- 12
- Pages:
- 1280–1281
- Publication date:
- 2018-11-12
- Acceptance date:
- 2018-10-04
- DOI:
- EISSN:
-
1529-2916
- ISSN:
-
1529-2908
Item Description
- Pubs id:
-
pubs:929149
- UUID:
-
uuid:2340d7ce-167b-437a-9415-ab6ddb3c423b
- Local pid:
- pubs:929149
- Source identifiers:
-
929149
- Deposit date:
- 2018-10-18
Terms of use
- Copyright holder:
- Dushek and Dustin
- Copyright date:
- 2018
- Notes:
- © Dushek and Dustin 2018. This is the accepted manuscript version of the article. The final version is available online from Springer Nature at: https://doi.org/10.1038/s41590-018-0261-5
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