Prevalence, determinants of positivity, and clinical utility of cryptococcal antigenemia in Cambodian HIV-infected patients.

Journal article

OBJECTIVES: To determine the prevalence, determinants ofpositivity, and clinical utility of serum cryptococcal polysaccharide (CPS) antigen testing among HIV-infected patients in 2004 in Cambodia, an area highly endemic for cryptococcosis. METHODS: All HIV-infected patients with a CD4+ count <200 cells/mm3 attending 1 of 2 Phnom Penh hospitals for the first time were systematically screened for serum CPS. Patients with positive test results were further investigated to identify those with...

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Authors: Micol, R; Lortholary, O; Sar, B; Laureillard, D; Ngeth, C

• Publication status: Published
• Journal: Journal of acquired immune deficiency syndromes (1999)
• Volume: 45
• Issue: 5
• Pages: 555-559
• Publication date: 2007-08-01
• DOI: 10.1097/qai.0b013e31811ed32c
• EISSN: 1944-7884
• ISSN: 1525-4135
• Language: English
• Keywords: Meningitis, Cryptococcal; Body Mass Index; Biological Markers; Male; AIDS-Related Opportunistic Infections; HIV; Female; Headache; Cambodia; Antigens, Fungal; Cohort Studies; Cryptococcosis; Cryptococcus neoformans; Risk Factors; Diagnosis, Differential; Humans; Adult; CD4 Lymphocyte Count; Prevalence; Prospective Studies