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Thesis

Three-dimensional recapitulation of neuroblastoma: from model to drug screening platform

Abstract:

Neuroblastoma is one of the most common yet fatal paediatric cancer. Nevertheless, few drug treatments are available in the market. One of the difficulties is the drug responses reported in 2-D in vitro tests does not always accurately reflect those observed in 3-D in vivo models. As the process consumes time, money and animal lives, a 3-D in vitro drug testing bioreactor recapitulating neuroblastoma tumours are needed to screen out any unsuccessful drug candidat...

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Division:
MSD
Role:
Author

Contributors

Department:
Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Supervisor
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Funding agency for:
Bovornchutichai, P
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Funding agency for:
Bovornchutichai, P
Grant:
EP/G036861/1
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:23322e1c-9e36-479f-bb84-1add6dd4c75f
Deposit date:
2019-01-30

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