Thesis
Three-dimensional recapitulation of neuroblastoma: from model to drug screening platform
- Abstract:
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Neuroblastoma is one of the most common yet fatal paediatric cancer. Nevertheless, few drug treatments are available in the market. One of the difficulties is the drug responses reported in 2-D in vitro tests does not always accurately reflect those observed in 3-D in vivo models. As the process consumes time, money and animal lives, a 3-D in vitro drug testing bioreactor recapitulating neuroblastoma tumours are needed to screen out any unsuccessful drug candidat...
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Authors
Contributors
+ Ye, H
Department:
Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford
Role:
Supervisor
+ O'Neill, E
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Supervisor
Funding
+ UK Research and Innovation
More from this funder
Funding agency for:
Bovornchutichai, P
Grant:
EP/G036861/1
+ China Regenerative Medicine International Limited
More from this funder
Funding agency for:
Bovornchutichai, P
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- UUID:
-
uuid:23322e1c-9e36-479f-bb84-1add6dd4c75f
- Deposit date:
- 2019-01-30
Terms of use
- Copyright holder:
- Bovornchutichai, P; . Phurit Bovornchutichai
- Copyright date:
- 2018
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