- Abstract:
-
Here we report a unique situation in which an early and synchronized Epstein-Barr virus (EBV) reactivation was induced by a 6-day course of treatment with a humanized CD3-specific monoclonal antibody in patients with recent onset of type 1 diabetes. The virologic and immunologic analysis demonstrated that this reactivation was transient, self-limited, and isolated, associated with the rapid advent of an EBV-specific T-cell response. The anti-CD3 antibody administration induced short-lasting i...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1182/blood-2009-02-204875
-
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- Journal:
- Blood
- Volume:
- 115
- Issue:
- 6
- Pages:
- 1145-1155
- Publication date:
- 2010-02-05
- DOI:
- EISSN:
-
1528-0020
- ISSN:
-
0006-4971
- URN:
-
uuid:2326342b-d94f-4bac-a13d-b0eba3992985
- Source identifiers:
-
49020
- Local pid:
- pubs:49020
- Language:
- English
- Keywords:
- Copyright date:
- 2010
Journal article
Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients.
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