Journal article
The two-year progression of structural and functional cerebral MRI in amyotrophic lateral sclerosis
- Abstract:
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MRI has emerged as one of several urgently needed candidate disease progression biomarkers for the neurodegenerative disorder amyotrophic lateral sclerosis (ALS), not least due to its unique ability to non-invasively assess structural and functional cerebral pathology. We sought to identify the extent of detectable change in cerebral MRI metrics over a more prolonged period. Analysis of multi-modal MRI data was performed in a cohort of sixteen patients (13 ALS and 3 with primary lateral scler...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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(pdf, 890.8KB)
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- Publisher copy:
- 10.1016/j.nicl.2017.12.025
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Authors
Funding
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- NeuroImage: Clinical Journal website
- Volume:
- 17
- Pages:
- 953-961
- Publication date:
- 2017-12-18
- Acceptance date:
- 2017-12-07
- DOI:
- ISSN:
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2213-1582
- Pubs id:
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pubs:810360
- URN:
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uri:231ce1b6-6dce-4ac8-a0bc-1a4061a42dfc
- UUID:
-
uuid:231ce1b6-6dce-4ac8-a0bc-1a4061a42dfc
- Local pid:
- pubs:810360
Terms of use
- Copyright holder:
- Menke et al.
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/BY/4.0/).
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