Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.

Cousminer, DL; Stergiakouli, E; Berry, DJ; Ang, W; Groen-Blokhuis, MM; Körner, A; Siitonen, N; Ntalla, I; Marinelli, M; Perry, JR; Kettunen, J; Jansen, R; Surakka, I; Timpson, NJ; Ring, S; Mcmahon, G; Power, C; Wang, C; Kähönen, M; Viikari, J; Lehtimäki, T; Middeldorp, CM; Hulshoff Pol, HE; Neef, M; Weise, S; Pahkala, K; Niinikoski, H; Zeggini, E; Panoutsopoulou, K; Bustamante, M; Penninx, BW; Murabito, J; Torrent, M; Dedoussis, GV; Kiess, W; Boomsma, DI; Pennell, CE; Raitakari, OT; Hyppönen, E; Davey Smith, G; Ripatti, S; McCarthy, MI; Widén, E

Abstract:

Little is known about genes regulating male puberty. Further, while many identified pubertal timing variants associate with age at menarche, a late manifestation of puberty, and body mass, little is known about these variants' relationship to pubertal initiation or tempo. To address these questions, we performed genome-wide association meta-analysis in over 11 000 European samples with data on early pubertal traits, male genital and female breast development, measured by the Tanner scale. We ...

Expand abstract

Publication status:

Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Cousminer, D. L., Stergiakouli, E., Berry, D. J., Ang, W., Groen-Blokhuis, M. M., Körner, A., Siitonen, N., Ntalla, I., Marinelli, M., Perry, J. R., Kettunen, J., Jansen, R., Surakka, I., Timpson, N. J., Ring, S., Mcmahon, G., Power, C., Wang, C., Kähönen, M., … Widén, E. (2014). Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Human Molecular Genetics, 23(16), 4452–4464.

MLA Style

Cousminer, D. L., et al. “Genome-Wide Association Study of Sexual Maturation in Males and Females Highlights a Role for Body Mass and Menarche Loci in Male Puberty.” Human Molecular Genetics, vol. 23, no. 16, Oxford University Press, 2014, pp. 4452–64.

Chicago Style

Cousminer, DL, E Stergiakouli, DJ Berry, W Ang, MM Groen-Blokhuis, A Körner, N Siitonen, et al. 2014. “Genome-Wide Association Study of Sexual Maturation in Males and Females Highlights a Role for Body Mass and Menarche Loci in Male Puberty.” Human Molecular Genetics 23 (16): 4452–64.
Tweet
Print