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Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.

Abstract:

Little is known about genes regulating male puberty. Further, while many identified pubertal timing variants associate with age at menarche, a late manifestation of puberty, and body mass, little is known about these variants' relationship to pubertal initiation or tempo. To address these questions, we performed genome-wide association meta-analysis in over 11 000 European samples with data on early pubertal traits, male genital and female breast development, measured by the Tanner scale. We ...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddu150

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Publisher:
Oxford University Press
Journal:
Human molecular genetics
Volume:
23
Issue:
16
Pages:
4452-4464
Publication date:
2014-08-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:2314593f-ddc5-435d-8d79-5b61789e4490
Source identifiers:
477706
Local pid:
pubs:477706

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