GABA(B) receptors at glutamatergic synapses in the rat striatum.

Journal article

Although multiple effects of GABA(B) receptor activation on synaptic transmission in the striatum have been described, the precise locations of the receptors mediating these effects have not been determined. To address this issue, we carried out pre-embedding immunogold electron microscopy in the rat using antibodies against the GABA(B) receptor subunits, GABA(B1) and GABA(B2). In addition, to investigate the relationship between GABA(B) receptors and glutamatergic striatal afferents, we used...

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Authors: Lacey, C; Boyes, J; Gerlach, O; Chen, L; Magill, P

• Journal: Neuroscience
• Volume: 136
• Issue: 4
• Pages: 1083-1095
• Publication date: 2005-01-01
• DOI: 10.1016/j.neuroscience.2005.07.013
• EISSN: 1873-7544
• ISSN: 0306-4522
• Language: English
• Keywords: Glutamic Acid; Blotting, Western; Corpus Striatum; Vesicular Glutamate Transport Protein 2; Male; Vesicular Glutamate Transport Protein 1; Neurons; Rats; Fluorescent Antibody Technique; Synapses; Animals; Rats, Sprague-Dawley; Microscopy, Immunoelectron; Receptors, GABA-B