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Renal prostaglandin synthesis in the Goldblatt hypertensive rat.

Abstract:

The role of prostaglandins in blood pressure regulation was studied in normal rats and in animals with renal artery constriction. The effects of chronic inhibition of prostaglandin (PG) synthesis on arterial pressure were observed, and renal medullary PG synthesis was measured in vitro. The prostaglandin synthetase inhibitor indomethacin was given in a dose of 2 mg/kg/day by mouth to one of two groups of male Wistar rats with a unilateral renal artery constriction and the other kidney untouch...

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Publication status:
Published

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Publisher copy:
10.1161/01.res.36.6.81

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Role:
Author
Journal:
Circulation research
Volume:
36
Issue:
6 Suppl 1
Pages:
81-88
Publication date:
1975-06-05
DOI:
EISSN:
1524-4571
ISSN:
0009-7330
URN:
uuid:2302d64b-e01e-479d-8bf8-c51b983c3675
Source identifiers:
41652
Local pid:
pubs:41652

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