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Journal article

Expression of mitochondrial TSPO and FAM173B is associated with inflammation and symptoms in patients with painful knee osteoarthritis

Abstract:

Objectives
To characterize the expression profiles of two nuclear-encoded mitochondrial genes previously associated with chronic pain, the translocator protein (TSPO) and family with sequence similarity 173B (FAM173B), in different knee compartments from patients with painful knee OA. Also, to examine their association with the joint expression of inflammatory cytokines/chemokines and clinical symptoms.

Methods
The study was performed on 40 knee OA patients and 19 postmortem ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/rheumatology/keaa565

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Publisher:
Oxford University Press
Journal:
Rheumatology More from this journal
Volume:
60
Issue:
4
Pages:
1724–1733
Publication date:
2020-10-17
Acceptance date:
2020-07-16
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
Language:
English
Keywords:
Pubs id:
1138290
Local pid:
pubs:1138290
Deposit date:
2020-10-19

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