The traditional notion that multiple sclerosis is a primary demyelinating disease has led to a plaque-centred view of both aetiology and the pathogenesis of disease progression. The presence of axonal loss has received increasing recognition. However, the relative roles of demyelination and axonal loss have not been fully clarified in multiple sclerosis nor have their possible interrelationships been elucidated. Post-mortem material from the cerebrum, brainstem and spinal cord of 55 multiple ...Expand abstract
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- G. C. DeLuca et al.
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- The full-text of this article is not currently available in ORA, but you may be able to access the article via the publisher copy link on this record page. Citation: DeLuca, G. C. et al. (2006). 'The contribution of demyelination to axonal loss in multiple sclerosis', Brain 129(6), 1507-1516. [The definitive publisher-authenticated version is available at http://brain.oxfordjournals.org].
The contribution of demyelination to axonal loss in multiple sclerosis
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