- Abstract:
-
Eosinophilic esophagitis (EoE) is a food allergy-associated inflammatory disease characterized by esophageal eosinophilia. Current management strategies for EoE are nonspecific, and thus there is a need to identify specific immunological pathways that could be targeted to treat this disease. EoE is associated with polymorphisms in the gene that encodes thymic stromal lymphopoietin (TSLP), a cytokine that promotes allergic inflammation, but how TSLP might contribute to EoE disease pathogenesis...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/nm.3281
-
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- Journal:
- Nature medicine
- Volume:
- 19
- Issue:
- 8
- Pages:
- 1005-1013
- Publication date:
- 2013-08-05
- DOI:
- EISSN:
-
1546-170X
- ISSN:
-
1078-8956
- URN:
-
uuid:22ea7bb4-4b70-490a-8441-bdbd86ab6036
- Source identifiers:
-
414329
- Local pid:
- pubs:414329
- Copyright date:
- 2013
Journal article
Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.
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