Peripheral DNA methylation, cognitive decline and brain ageing: Pilot findings from the Whitehall II Imaging Study
DNA methylation (DNAm) has been linked with the pathophysiology of brain aging, cognitive impairment and dementia.
The present study investigated the association between blood genome-wide DNAm profiles, cognitive dysfunction and brain magnetic resonance imaging (MRI) measures in 48 participants of the Whitehall II imaging sub-study.
We identified eight differentially methylated regions (DMRs) associated with cognitive imp...Expand abstract
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- Peer reviewed
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- Leonidas Chouliaras
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- © Leonidas Chouliaras. This work is licensed under the Attribution-NonCommercial-NoDerivatives 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
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