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Journal article

Discovery and fine mapping of serum protein loci through transethnic meta-analysis.

Abstract:

Many disorders are associated with altered serum protein concentrations, including malnutrition, cancer, and cardiovascular, kidney, and inflammatory diseases. Although these protein concentrations are highly heritable, relatively little is known about their underlying genetic determinants. Through transethnic meta-analysis of European-ancestry and Japanese genome-wide association studies, we identified six loci at genome-wide significance (p < 5 × 10(-8)) for serum albumin (HPN-SCN1B, GCK...

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Publication status:
Published

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Publisher copy:
10.1016/j.ajhg.2012.08.021

Authors


Franceschini, N More by this author
van Rooij, FJ More by this author
Feitosa, MF More by this author
Karakas, M More by this author
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Journal:
American journal of human genetics
Volume:
91
Issue:
4
Pages:
744-753
Publication date:
2012-10-05
DOI:
EISSN:
1537-6605
ISSN:
0002-9297
URN:
uuid:22dbc3d8-0b5a-43f3-9908-4506af00222c
Source identifiers:
356635
Local pid:
pubs:356635

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