- Abstract:
-
Many disorders are associated with altered serum protein concentrations, including malnutrition, cancer, and cardiovascular, kidney, and inflammatory diseases. Although these protein concentrations are highly heritable, relatively little is known about their underlying genetic determinants. Through transethnic meta-analysis of European-ancestry and Japanese genome-wide association studies, we identified six loci at genome-wide significance (p < 5 × 10(-8)) for serum albumin (HPN-SCN1B, GCK...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.ajhg.2012.08.021
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- Journal:
- American journal of human genetics
- Volume:
- 91
- Issue:
- 4
- Pages:
- 744-753
- Publication date:
- 2012-10-05
- DOI:
- EISSN:
-
1537-6605
- ISSN:
-
0002-9297
- URN:
-
uuid:22dbc3d8-0b5a-43f3-9908-4506af00222c
- Source identifiers:
-
356635
- Local pid:
- pubs:356635
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
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