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Suggestive linkage of the parathyroid receptor type 1 to osteoporosis.

Abstract:

We have investigated the role of 23 candidate genes in the control of bone mineral density (BMD) by linkage studies in families of probands with osteoporosis (lumbar spine [LS] or femoral neck [FN] BMD T score < -2.5) and low BMD relative to an age- and gender-matched cohort (Z score < -2.0). One hundred and fifteen probands (35 male, 80 female) and 499 of their first- or second-degree relatives (223 males and 276 females) were recruited for the study. BMD was measured at the LS and FN ...

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Journal:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Volume:
14
Issue:
12
Pages:
1993-1999
Publication date:
1999-12-05
DOI:
EISSN:
1523-4681
ISSN:
0884-0431
URN:
uuid:22a9ee06-0484-4d90-a5a9-314829cc9580
Source identifiers:
95853
Local pid:
pubs:95853

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