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Conference item : Abstract

Ten year follow up case control study of the effect of portal vein embolization (PVE) on the survival of patients with colorectal liver metastases (CRLM) and the influence of hypoxia factors on tumour growth

Abstract:
PVE facilitates hepatectomy in patients with a small anticipated future liver remnant, but stimulates tumour growth. Hypoxia may mediate this increased tumour growth as Hypoxia-Inducible-Factor-1a (HIF-1a) increases angiogenesis, invasion and other Hallmarks of Cancer. This study investigates the relationship of patient survival to expression of HIF-1a and other hypoxia factors regulated in resected CRLM, in a case control study, comparing patients with and without PVE.
Publication status:
Published
Peer review status:
Reviewed (other)

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Publisher copy:
10.1016/j.hpb.2016.02.014

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Clinical Laboratory Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Clinical Laboratory Sciences
Role:
Author
Publisher:
Elsevier
Host title:
HPB
Journal:
12th World Congress of the International Hepato-Pancreato-Biliary Association More from this journal
Volume:
18
Issue:
S1
Pages:
e3
Publication date:
2016-04-19
Acceptance date:
2015-11-20
DOI:
ISSN:
0007-1323
Subtype:
Abstract
Pubs id:
pubs:623983
UUID:
uuid:229d9a4f-92ff-44d2-a89d-94d8e2581e0f
Local pid:
pubs:623983
Source identifiers:
623983
Deposit date:
2017-06-14

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