Journal article icon

Journal article

Androgen regulates ADAMTS15 gene expression in prostate cancer cells.

Abstract:

Prostate cancer is a major cause of mortality, largely as a consequence of metastases and transformation to androgen-independent growth. Metalloproteinases are implicated in cancer progression. A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) are expressed in prostate cancer cells, with ADAMTS-1 and ADAMTS-15 being the most abundant. ADAMTS-15 but not ADAMTS-1 expression was downregulated by androgen in LNCaP prostate cancer cells, possibly through androgen response ele...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Molokwu, CN More by this author
Adeniji, OO More by this author
Chandrasekharan, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences, Biomedical Research Centre
Buttle, DJ More by this author
Journal:
Cancer investigation
Volume:
28
Issue:
7
Pages:
698-710
Publication date:
2010-08-05
DOI:
EISSN:
1532-4192
ISSN:
0735-7907
URN:
uuid:229b2ce5-9543-47cc-83a5-01e1b0c59a11
Source identifiers:
120641
Local pid:
pubs:120641

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP