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Journal article

Androgen regulates ADAMTS15 gene expression in prostate cancer cells.

Abstract:

Prostate cancer is a major cause of mortality, largely as a consequence of metastases and transformation to androgen-independent growth. Metalloproteinases are implicated in cancer progression. A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) are expressed in prostate cancer cells, with ADAMTS-1 and ADAMTS-15 being the most abundant. ADAMTS-15 but not ADAMTS-1 expression was downregulated by androgen in LNCaP prostate cancer cells, possibly through androgen response ele...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
Journal:
Cancer investigation
Volume:
28
Issue:
7
Pages:
698-710
Publication date:
2010-08-01
DOI:
EISSN:
1532-4192
ISSN:
0735-7907
Source identifiers:
120641
Language:
English
Keywords:
Pubs id:
pubs:120641
UUID:
uuid:229b2ce5-9543-47cc-83a5-01e1b0c59a11
Local pid:
pubs:120641
Deposit date:
2012-12-19

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