- Abstract:
-
Prostate cancer is a major cause of mortality, largely as a consequence of metastases and transformation to androgen-independent growth. Metalloproteinases are implicated in cancer progression. A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) are expressed in prostate cancer cells, with ADAMTS-1 and ADAMTS-15 being the most abundant. ADAMTS-15 but not ADAMTS-1 expression was downregulated by androgen in LNCaP prostate cancer cells, possibly through androgen response ele...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.3109/07357907.2010.489538
-
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- Journal:
- Cancer investigation
- Volume:
- 28
- Issue:
- 7
- Pages:
- 698-710
- Publication date:
- 2010-08-05
- DOI:
- EISSN:
-
1532-4192
- ISSN:
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0735-7907
- URN:
-
uuid:229b2ce5-9543-47cc-83a5-01e1b0c59a11
- Source identifiers:
-
120641
- Local pid:
- pubs:120641
- Copyright date:
- 2010
Journal article
Androgen regulates ADAMTS15 gene expression in prostate cancer cells.
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