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Ultrafast magnetic resonance imaging for iron quantification in thalassemia participants in the developing world: The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR).

Abstract:

Thalassemia is the most common monogenetic disorder worldwide, with 60 000 infants with thalassemia major born annually.1 Survival often depends on regular blood transfusions to correct anemia and to reduce ineffective erythropoiesis, but these transfusions can result in iron overload and organ failure unless chelation therapy is undertaken. Serum ferritin levels continue to be used as a guide to chelation but are unreliable, and the availability of cardiovascular magnetic resonance (CMR) ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


More from this funder
Name:
Chulalongkorn University
Grant:
RA58/058
More from this funder
Name:
National Institute for Health Research
Funding agency for:
Piechnik, S
Publisher:
American Heart Association
Journal:
Circulation More from this journal
Volume:
134
Issue:
5
Pages:
432-434
Publication date:
2016-08-01
Acceptance date:
2016-05-19
DOI:
ISSN:
0009-7322 and 1524-4539
Pmid:
27482005
Language:
English
Keywords:
Pubs id:
pubs:638887
UUID:
uuid:229a5b26-5cca-4265-9363-07980ef37b86
Local pid:
pubs:638887
Source identifiers:
638887
Deposit date:
2017-03-24

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