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A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice.

Abstract:

Whole-genome genetic association studies in outbred mouse populations represent a novel approach to identifying the molecular basis of naturally occurring genetic variants, the major source of quantitative variation between inbred strains of mice. Measuring multiple phenotypes in parallel on each mouse would make the approach cost effective, but protocols for phenotyping on a large enough scale have not been developed. In this article we describe the development and deployment of a protocol t...

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Publication status:
Published

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Publisher copy:
10.1007/s00335-005-0112-1

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Mammalian genome : official journal of the International Mammalian Genome Society
Volume:
17
Issue:
2
Pages:
129-146
Publication date:
2006-02-01
DOI:
EISSN:
1432-1777
ISSN:
0938-8990
Source identifiers:
4709

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