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Ab initio identification of novel regulatory elements in the genome of Trypanosma brucei by Bayesioan inference on sequence segmentation

Abstract:

The rapid increase in the availability of genome information has created considerable demand for both comparative and ab initio predictive bioinformatic analyses. The biology laid bare in the genomes of many organisms is often novel, presenting new challenges for bioinformatic interrogation. A paradigm for this is the collected genomes of the kinetoplastid parasites, a group which includes Trypanosoma brucei the causative agent of human African trypanosomiasis. These genomes, though outwardly...

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Publication date:
2011-01-01
UUID:
uuid:227ffd55-7fdd-4b95-b70f-58d5c5cfc210
Local pid:
oai:eprints.maths.ox.ac.uk:1403
Deposit date:
2011-10-06

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