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Serum and mucosal antibody responses to pneumococcal protein antigens in children: relationships with carriage status.

Abstract:

Streptococcus pneumoniae causes significant morbidity and mortality especially in children. Some pneumococcal protein antigens can protect mice against infection. Little information is available concerning the nature of naturally acquired protective immunity to pneumococci in humans induced by these antigens. This study investigates the relationships between systemic and local antibody production and carriage in children. Children undergoing adenoidectomy (n=112, ages 2-12 years) were studied...

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Publication status:
Published

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Publisher copy:
10.1002/eji.200535101

Authors


Bernatoniene, J More by this author
Bagrade, L More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics, Biomedical Research Centre
Mitchell, TJ More by this author
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Journal:
European journal of immunology
Volume:
36
Issue:
1
Pages:
46-57
Publication date:
2006-01-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:227c087f-1362-493b-8b81-2e7b4becc249
Source identifiers:
119529
Local pid:
pubs:119529

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