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Identification of four trp1 gene variants murine pancreatic beta-cells.

Abstract:

Insulin secretion is stimulated by glucose, hormones and neurotransmitters. Both activation of a non-selective cation current and activation of a Ca2+ current in response to depletion of intracellular Ca2+ stores have been suggested to play a role in this stimulation. The properties of these currents resemble those reported for the Drosophila genes trp and trpl. Using the reverse transcription polymerase chain reaction and Northern blot analysis we found that of the six mammalian trp-related ...

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Publication status:
Published

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Publisher copy:
10.1007/s001250050711

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Journal:
Diabetologia More from this journal
Volume:
40
Issue:
5
Pages:
528-532
Publication date:
1997-05-01
DOI:
EISSN:
1432-0428
ISSN:
0012-186X

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