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Journal article

Chromosomes with one, two, three, and four fetal globin genes: molecular and hematologic analysis.

Abstract:

Analysis of DNA from 852 Island Melanesians has revealed a high frequency of single- and triple-gamma-globin genes in this population. Homozygotes for triple- and single-gamma genes have normal hematologic findings, normal hemoglobin F (HbF) levels, and when there is coexisting alpha thalassemia, appropriate levels of Bart's Hb (gamma 4) at birth. In addition, we have identified an individual with a quadruple-gamma gene chromosome who also has a normal HbF level. All single-gamma genes were A...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
Journal:
Blood More from this journal
Volume:
67
Issue:
6
Pages:
1611-1618
Publication date:
1986-06-01
EISSN:
1528-0020
ISSN:
0006-4971
Language:
English
Keywords:
Pubs id:
pubs:95421
UUID:
uuid:227bba8c-9a1f-4813-86f6-61f986a6dc58
Local pid:
pubs:95421
Source identifiers:
95421
Deposit date:
2012-12-19

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