Thesis icon

Thesis

The interaction between HTLV-1 Tax protein and the proteasome

Abstract:

This thesis presents studies on the interaction between the human T cell lymphotropic virus type 1 (HTLV-1) Tax protein and the 20S proteasome and the role of the interaction in cellular processes and the cytotoxic T cell (CTL) response against HTLV-1.

The rapid translocation of Tax into the nucleus is described. Tax accumulates in the nucleus and forms unique bodies involved in transcriptional activation.

It was further found that Tax associated with assembled nuclear 20S p...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2001
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
UUID:
uuid:22772f94-dd13-4448-8cc8-26371cc1b169
Local pid:
td:603836279
Source identifiers:
603836279
Deposit date:
2013-01-18

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP