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Characterization of lymphocytic choriomeningitis virus-binding protein(s): a candidate cellular receptor for the virus.

Abstract:

The attachment of lymphocytic choriomeningitis virus (LCMV) to murine and primate cell lines was quantitated by a fluorescence-activated cell sorter assay in which binding of biotinylated virus was detected with streptavidin-fluorescein isothiocyanate. Cell lines that were readily infected by LCMV (e.g., MC57, Rin, BHK, Vero, and HeLa) bound virus in a dose-dependent manner, whereas no significant binding was observed to lymphocytic cell lines (e.g., RMA and WIL 2) that were not readily infec...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Oldstone, MB More by this author
Journal:
Journal of virology
Volume:
66
Issue:
12
Pages:
7270-7281
Publication date:
1992-12-05
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:2246ae4b-7a67-4b54-93fe-6bb28ab3d08b
Source identifiers:
32463
Local pid:
pubs:32463

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