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Thesis

Studies on basement membrane permeation

Alternative title:
models of pathogenic mechanisms of glomerulonephritis
Abstract:

The effects of the biological cross-linker transglutaminase, the neutrophil oxidant hydrogen peroxide, and neutrophil proteinases on glomerular basement membrane permeability have been examined using an in vitro model of glomerular ultrafiltration. The main focus of the study lies in determining whether any of the test agents were able to render glomerular basement membrane more permeable to protein.

Guinea pig liver transglutaminase was used as a model enzyme to test for the effec...

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Institution:
University of Oxford
Department:
Faculty of Biological Sciences Division
Role:
Author

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Role:
Supervisor
Role:
Supervisor
Publication date:
1994
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
UUID:
uuid:22440bfc-e712-4f7c-a11d-2eed9b07bcb6
Local pid:
td:603851146
Source identifiers:
603851146
Deposit date:
2014-07-22

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