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In vitro responses of human CD45R0brightRA- and CD45R0-RAbright T cell subsets and their relationship to memory and naive T cells.

Abstract:

The cellular basis of immunological memory, particularly with respect to T cells is not understood. In humans, monoclonal antibodies to CD45 have been used to identify memory (CD45R0) and naive (CD45RA) T cells. However, this identification has been called into question by various studies which suggest that high molecular weight CD45 isoforms may be re-expressed by previously activated cells. In the present study, using cultures which supported responses of naive T cells, we examined the resp...

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Publisher copy:
10.1002/eji.1830270937

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
European journal of immunology More from this journal
Volume:
27
Issue:
9
Pages:
2383-2390
Publication date:
1997-09-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Language:
English
Keywords:
Pubs id:
pubs:36101
UUID:
uuid:223947a4-f98b-4c8b-aaac-c98639085f8b
Local pid:
pubs:36101
Source identifiers:
36101
Deposit date:
2012-12-20

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