Journal article
Redundancy and evolution of GATA factor requirements in development of the myocardium.
- Abstract:
-
The transcription factors, GATA4, 5 and 6, recognize the same DNA sequence and are all expressed in the developing myocardium. However, knockout studies in the mouse have indicated that none of them are absolutely required for the specification of the myocardium. Here we present evidence for redundancy in this family for the first time. Using morpholinos in both Xenopus and zebrafish embryos, we show that GATA4 knockdown, for example, only affects cardiac marker expression in the absence of e...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.ydbio.2007.08.018
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Authors
Bibliographic Details
- Journal:
- Developmental biology
- Volume:
- 311
- Issue:
- 2
- Pages:
- 623-635
- Publication date:
- 2007-11-01
- DOI:
- EISSN:
-
1095-564X
- ISSN:
-
0012-1606
- Source identifiers:
-
106458
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:106458
- UUID:
-
uuid:2232c2f1-c7b2-45ac-8798-c7f6c1a6c850
- Local pid:
- pubs:106458
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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