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The resistance to physiological shear stresses of the erythrocytic rosettes formed by cells infected with Plasmodium falciparum.

Abstract:

Rosetting forces are believed to be an important contributor to the microcirculatory obstruction that occurs in malaria caused by Plasmodium falciparum. In this study, rosettes of erythrocytes from cultures of this parasite were suspended in different media and exposed to shear stresses corresponding to those encountered on the arterial and venous sides of the human circulation. The rosettes formed by infected erythrocytes in malaria culture medium containing 10% AB serum were disrupted easil...

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Publication status:
Published

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Publisher copy:
10.1080/00034980050006384

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
Annals of tropical medicine and parasitology More from this journal
Volume:
94
Issue:
3
Pages:
219-226
Publication date:
2000-04-01
DOI:
EISSN:
1364-8594
ISSN:
0003-4983
Language:
English
Keywords:
Pubs id:
pubs:31715
UUID:
uuid:2219e3e1-7ed1-4e8a-9156-e7e92d0c2f26
Local pid:
pubs:31715
Source identifiers:
31715
Deposit date:
2012-12-19

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