Journal article icon

Journal article

Influence of luminescence quantum yield, surface coating, and functionalization of quantum dots on the sensitivity of time-resolved FRET bioassays.

Abstract:

In clinical diagnostics, homogeneous time-resolved (TR) FRET immunoassays are used for fast and highly sensitive detection of biomarkers in serum samples. The most common immunoassay format is based on europium chelate or cryptate donors and allophycocyanin acceptors. Replacing europium donors with terbium complexes and the acceptors with QDs offers large photophysical advantages for multiplexed diagnostics, because the Tb-complex can be used as FRET donor for QD acceptors of different colors...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1021/am3030728

Authors


Expand authors...
Journal:
ACS applied materials and interfaces
Volume:
5
Issue:
8
Pages:
2881-2892
Publication date:
2013-04-05
DOI:
EISSN:
1944-8252
ISSN:
1944-8244
URN:
uuid:2216aca1-b700-4a6f-82c6-c7b199eba967
Source identifiers:
404983
Local pid:
pubs:404983

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP